Despite the subjective satisfaction of patients in many studies, the increase in the thickness of the skin and the improvement in wrinkles at different scales Alvera Tone Review, there is a lack of data on the long-term efficacy due to the patients’ subsequent cosmetic interventions.
Autologous fat: the adipose tissue is an ideal source of stromal stem cells, and by cultivating and transplanting it, long-term results are obtained, since these stem cells can be differentiated into fibroblasts or adipocytes restoring the lost volume.
Around 32% of the volume injected remains after 16 months. Collagen: Bovine collagen has been used for more than two decades as a biomaterial. Among its adverse effects are hypersensitivity Alvera Tone Review, ecchymosis, reactivation of herpesviruses, bacterial infection and local necrosis.